Yeast Programed Cell Death and Aging
نویسندگان
چکیده
منابع مشابه
Yeast Programed Cell Death and Aging
Similarly to metazoans, yeast cells can exhibit several characteristics of apoptosis, including chromatin condensation, DNA breakage,flipping of phosphatidylserine to the outer leaflet of the plasma membrane, accumulation of reactive oxygen species (ROS), and release of pro-death factors such as cytochrome c or Endonuclease G from mitochondria. Yeast programed cell death has been shown to occur...
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1 Pasteur Institute-Cenci Bolognetti Foundation, Department of Biology and Biotechnology Charles Darwin Sapienza, University of Rome, 00185 Rome, Italy 2 National Research Council-Institute of Biomembranes and Bioenergetics, Via Amendola 165/a, 70126 Bari, Italy 3 Functional Biology, KU Leuven, Kasteelpark Arenberg 31, 3001 Heverlee, Belgium 4Life and Health Sciences Research Institute, School ...
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Mitochondria play crucial roles in programmed cell death and aging. Different stimuli activate distinct mitochondrion-dependent cell death pathways, and aging is associated with a progressive increase in mitochondrial damage, culminating in oxidative stress and cellular dysfunction. Mitochondria are highly dynamic organelles that constantly fuse and divide, forming either interconnected mitocho...
متن کاملApproaches to study yeast cell aging and death.
For millennia, yeast has been exploited to obtain fermentation products, such as foods and beverages. For c. 50 years, yeast has been an established model organism for basic and applied research, and more specifically, for c. 15 years, this unicellular organism has been applied to dissect molecular mechanisms of cell aging and programmed cell death. In this review, we present an overview of app...
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ژورنال
عنوان ژورنال: Frontiers in Oncology
سال: 2013
ISSN: 2234-943X
DOI: 10.3389/fonc.2013.00283